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Co-participation of paternal and maternal genomes before the blastocyst stage is not required for full-term development of mouse embryos Free
Xin Li1,2,†, Jia-Qiang Wang1,†, Le-Yun Wang1,2,†, Hai-Feng Wan2, Yu-Fei Li2, Tian-Da Li2, Yu-Kai Wang2, Ling Shuai2, Yi-Huan Mao2,3, Xiao-Long Cui2, Liu Wang2, Zhong-Hua Liu1, Wei Li2, and Qi Zhou1,2,*
1College of Life Sciences, Northeast Agricultural University, Harbin 150030, China
2State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China
3University of Chinese Academy of Sciences, Beijing 100049, China *Correspondence to:Qi Zhou, E-mail: qzhou@ioz.ac.cn
J Mol Cell Biol, Volume 7, Issue 5, October 2015, 486-488,  https://doi.org/10.1093/jmcb/mjv055

The development of all the mammalian species begins from fertilization of a sperm and an egg into a diploid state. The maternal and paternal genomes are not functionally equivalent in term of their differential contributions to the imprinting gene expressions, and they are complementary and both essential for embryonic and postnatal development (McGrath and Solter, 1984; Surani et al., 1986).